DIROXIMEL INTERMEDIATE BY A.R LIFE SCIENCE

Diroximel Intermediate By A.R Life Science

Diroximel Intermediate By A.R Life Science

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Diroximel Intermediate: N-(2-Hydroxyethyl)succinimide and Its Role in Neurological Treatments

Pharmaceutical intermediates serve as the foundation for creating life-changing medications. Among these, N-(2-Hydroxyethyl)succinimide, bearing CAS No. 18190-44-8, is a critical compound in synthesizing Diroximel Fumarate, a drug for treating multiple sclerosis (MS).

This blog explores the properties, mechanism of action, therapeutic applications, and the indispensable role of A.R. Life Sciences Pvt. Ltd., a leading manufacturer of high-quality pharmaceutical intermediates, in producing N-(2-Hydroxyethyl)succinimide.


  • Overview of N-(2-Hydroxyethyl)succinimide

  • Chemical Name: N-(2-Hydroxyethyl)succinimide

  • CAS Number: 18190-44-8

  • Molecular Formula: C6H9NO3

  • Molecular Weight: 143.14 g/mol


Properties


Appearance: White crystalline powder.

Solubility: Soluble in distilled water and organic solvents like methanol and ethanol.

Stability: Stable under standard conditions; sensitive to prolonged exposure to heat and moisture.

A.R. Life Sciences Pvt. Ltd. manufactures N-(2-Hydroxyethyl)succinimide with exceptional purity and consistency. It is a dependable option for pharmaceutical companies around the globe.

Role in Diroximel Fumarate Synthesis


N-(2-Hydroxyethyl)succinimide is an essential intermediate in synthesizing Diroximel Fumarate, a prodrug of monomethyl fumarate (MMF). Its unique chemical structure is integral to forming the active molecule that provides therapeutic benefits in managing multiple sclerosis.

Mechanism of Action of Diroximel Fumarate


Diroximel Fumarate regulates the immune response to decrease inflammation and protect nerve cells from damage.

Activation of the Nrf2 Pathway: Improves the expression of antioxidant proteins, which protect against oxidative stress and inflammation in neurons.

Reduction of Immune Response: Lowers the activity of immune cells, which attacks the central nervous system, a hallmark of multiple sclerosis.

Neuroprotection: Minimizes further damage to nerve cells, aiding in managing disease progression.

Therapeutic Applications

Diroximel Fumarate, synthesized using N-(2-Hydroxyethyl)succinimide, is

Primarily used to treat:

Relapsing-Remitting Multiple Sclerosis (RRMS)

Decreases relapse frequency and slows the advancement of physical disability in MS patients.

Management of Inflammation


This helps manage the inflammatory response contributing to multiple sclerosis nerve damage.

The availability of high-quality N-(2-Hydroxyethyl)succinimide, as produced by A.R. Life Sciences Pvt. Ltd., ensures that Diroximel Fumarate remains a reliable option for patients and healthcare providers.

A.R. Life Sciences Pvt. Ltd.: Driving Pharmaceutical Excellence

As a leader in pharmaceutical intermediate manufacturing, A.R. Life Sciences Pvt. Ltd. is at the forefront of innovation and quality. Their expertise in producing N-(2-Hydroxyethyl)succinimide (CAS No. 18190-44-8) ensures a consistent supply of this crucial intermediate to the global pharmaceutical market.

Key Strengths of A.R. Life Sciences Pvt. Ltd.



  • Advanced manufacturing capabilities to produce high-purity intermediates.

  • Rigorous quality control processes that adhere to international pharmaceutical standards.

  • Commitment to delivering innovative solutions that drive medical advancements.

  • By partnering with pharmaceutical manufacturers, A.R. Life Sciences Pvt. Ltd. plays a pivotal role in ensuring the availability of life-saving medications like Diroximel Fumarate.


Conclusion


N-(2-Hydroxyethyl)succinimide (CAS No. 18190-44-8) is an essential intermediate in the production of Diroximel Fumarate, a medication that transforms the lives of multiple sclerosis patients. Its high-quality production ensures this vital drug's safety, efficacy, and reliability.

A.R. Life Sciences Pvt. Ltd., with its dedication to innovation and excellence, ensures the global availability of N-(2-Hydroxyethyl)succinimide, empowering pharmaceutical companies to create medications that improve lives. The consistent quality and reliability provided by A.R. Life Sciences Pvt. Ltd. make them a trusted name in the industry, supporting advancements in healthcare worldwide.

By choosing A.R. Life Sciences Pvt. Ltd., pharmaceutical companies gain access to top-tier intermediates crucial for producing effective therapies, reaffirming their role as a leader in the pharmaceutical manufacturing landscape.

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